Clomiphene Citrate is a selective estrogen receptor modulator (SERM) that works by blocking estrogen receptors in the brain, particularly in the hypothalamus. By doing so, it tricks the body into thinking that estrogen levels are low, leading to an increase in the production of follicle-stimulating hormone (FSH) and luteinizing hormone (LH). These hormones are crucial for stimulating the ovaries in women and increasing testosterone production in men. Clomiphene Citrate is most commonly used by athletes and bodybuilders during post-cycle therapy to help restart natural testosterone production after a cycle of anabolic steroids.

Post-Cycle Therapy (PCT) for Men: week 1: 50–100 mg per day

week 2–4: 25–50 mg per day

Fertility Treatment for Women (as prescribed):

50 mg per day for 5 days, starting on the 3rd, 4th, or 5th day of the menstrual cycle.

Dosage can be increased to 100 mg per day in subsequent cycles if ovulation does not occur.

Cycle Length:

For PCT: Typically 4 weeks.

For fertility treatment: Up to 3 consecutive cycles, as prescribed by a doctor.

Clomiphene Citrate is typically taken orally in tablet form. The dosage and duration of use depend on the purpose of the treatment. For post-cycle therapy in men, a common dosage is 50 mg per day for 4 to 6 weeks, starting shortly after the end of the steroid cycle. In women undergoing fertility treatment, the usual dosage is 50 mg per day for 5 days, starting on the third or fifth day of the menstrual cycle. The dose may be adjusted based on the individual’s response and the recommendation of a healthcare professional.

It is important to follow the prescribed dosage and duration of use carefully and not exceed the recommended amount to minimize the risk of side effects. Regular monitoring and follow-up with a healthcare provider are essential to ensure the safe and effective use of Clomiphene Citrate.

While Clomiphene Citrate is generally well-tolerated, some users may experience side effects:

Visual Disturbances: some users may experience visual disturbances such as blurred vision, floaters, or flashes of light. These effects are usually temporary and resolve after discontinuation of the medication but should be monitored closely.

Mood Swings and Emotional Changes: clomiphene Citrate can affect mood and emotions, leading to mood swings, irritability, or feelings of anxiety. These side effects are typically mild and temporary but can be more pronounced in some individuals.

Hot Flashes and Sweating: hot flashes and increased sweating are common side effects of Clomiphene Citrate, particularly in women undergoing fertility treatment. These effects are due to hormonal fluctuations and usually subside after the treatment period.

Gastrointestinal Discomfort: some users may experience mild gastrointestinal discomfort, including nausea, bloating, or abdominal pain. These symptoms are typically mild and can be managed with dietary adjustments.

Risk of Multiple Pregnancies: when used for fertility treatment, Clomiphene Citrate increases the risk of multiple pregnancies (twins or more). This is due to the stimulation of multiple follicles, which can lead to the release of more than one egg.

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